Monday, 14 March 2016

Stripping donor hearts and repopulating them with recipient-derived stem cells



Heart transplants have been around since 1967, but they're still anything but routine. In an effort to ensure a steady supply of compatible organs, a team of scientists from Massachusetts General Hospital (MGH) is working on ways to create bioengineered human hearts by first stripping donor hearts of cells that could provoke an immune response in a potential recipient, and then using the recipient's own induced pluripotent stem cells (iPSCs) to generate cardiac muscle cells that can be used to repopulate the heart in an automated bioreactor system.

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Category: Medical

Tags:
Heart
Transplant
Massachusetts General Hospital

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